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Built from 3 sources · one instruction: “compare the regulatory steps”

Enzyme
Role
Regulation
Source
Hexokinase
Phosphorylates glucose to glucose-6-phosphate
Inhibited by its product, glucose-6-phosphate
Ch. 3 · p. 41
PFK-1
Commits fructose-6-phosphate to glycolysis
Inhibited by ATP; activated by AMP and F-2,6-BP
Ch. 3 · p. 44
Aldolase
Splits F-1,6-BP into two triose phosphates
Not a regulated step
Ch. 3 · p. 46
GAPDH
Oxidises and phosphorylates glyceraldehyde-3-phosphate
Controlled by the NAD⁺ / NADH ratio
Ch. 3 · p. 49
extracting from textbook-ch3.pdf…

The scattered version

…PFK-1 is inhibited by ATP

p. 44

…hexokinase is blocked by its own glucose-6-phosphate

p. 41

…GAPDH depends on the NAD⁺ / NADH ratio

p. 49

three chapters apart

The comparable version

Enzyme
Regulation
PFK-1
Inhibited by ATP
Hexokinase
Inhibited by G6P

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Enzymes & their regulators

The step, what turns it up, what shuts it down — the comparison biochemistry exams live on.

Dates, treaties, causes

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Cases & their holdings

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